Inhibition of Uncoupling Protein 2 Attenuates Cardiac Hypertrophy Induced by Transverse Aortic Constriction in Mice
Background: Uncoupling protein 2 (UCP2) is critical in regulating VITAMIN D CONC.DROPS energy metabolism.Due to the significant change in energy metabolism of myocardium upon pressure overload, we hypothesize that UCP2 could contribute to the etiology of cardiac hypertrophy.Methods: Adult male C57BL/6J mice were subjected to pressure overload by us